0262 Comparing Wrist Actigraphy to a Novel Wearable (Actigpatch): Nonparametric Activity Estimation

Abstract Introduction Wrist actigraphy is a standard for monitoring sleep in the field; however, data quality reduced if participants remove device. The Actigpatch novel, adhesive water-resistant wearable that we have previously demonstrated as comparable to wrist traditional sleep-wake estimation. Here compare assessment of nonparametric activity indexes. Methods While following fixed schedules, 39 simultaneously wore Micro Motionlogger actigraph (Ambulatory Monitoring Inc., Ardley, NY) on their non-dominant and (Circadian Positioning Systems, Newport, RI) over triceps dominant arm. Our analyses included 35 (21F; 32.9±13.2yrs) who contributed ≥four nights (range: 4-14 [mean: 10] nights). After matching devices’ tri-axial actimetry one-minute epochs, derived key non-parametric parameters diurnal calculated intraclass correlations measure agreement. include interdaily stability (IS), intradaily variability (IV), timing five hours lowest (L5onset) ten highest (M10onset), overall relative amplitude (RA). Results We observed agreement ranging from good IS (ICC=0.77 [95%CI=0.59;0.88]; [all mean differences are patch-watch] difference=-0.21) poor IV (ICC=0.43 [0.12;0.67]; difference=0.29). ICC showed M10onset (ICC=0.82 [0.67; 0.90]; difference=-37min) excellent L5onset (ICC=0.91 [0.82;0.95]; difference=-2min). Finally, identified when estimating (RA ICC=0.86 [0.75; 0.93]; difference=0.03). An example was manifested close estimation (patch mean=1:04am, SD=70min; watch mean=1:06am, SD=68min). Conclusion Adding our prior evidence these two devices offer similar using algorithms, present indicate offers IS, timing, RA. Agreement not IV, with showing more than watch, perhaps due placement. Because unobtrusive, water-resistant, can be worn continuously three weeks, it has potential benefits studies individuals struggle adherence wearing devices. Support (if any) R01AA025593, P20GM139743. Actigpatches provided by Circadian Systems.